Pregenius. Een slimme kijk op uw gezondheid

Literatuuroverzicht

MET BETREKKING TOT CARDIOVASULAIRE RISICO’S

BLOEDDRUK
Hammoud RA, Vaccari CS, Nagamia SH, Khan BV. Regulation of the renin-angiotensin system in coronary atherosclerosis: a review of the literature. Vasc Health Risk Manag. (2007); 3: 937-945.
Cha SH, Kim HT, Jang Y, Park S, Kim JJ, Song MY, Park JH, Ryu HJ, Park HY, Yoon SJ, Kimm K, Lee JK, Oh B. Association of alpha-adducin Gly460Trp polymorphism with coronary artery disease in a Korean population.Journal of hypertension Publish.(2007); 25: 2413-2420.

Freitas AI, Mendonça I, Brió M, Sequeira MM, Reis RP, Carracedo A, Brehm A. RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population. BMC cardiovascular disorders.(2008); 8: 15.

Mendonça MI, Dos Reis RP, Freitas AI, Sousa AC, Pereira A, Faria P, Gomes S, Silva B, Santos N, Serrao M, Ornelas I, Freitas S, Freitas C, Araújo JJ, Brehm A, Cardoso AA. Gene-gene interaction affects coronary artery disease risk.Rev Port Cardiol. (2009); 28: 397-415.

OXIDATIEVE STRESS
Stocker R, Keaney,JF. Role of oxidative modifications in atherosclerosis. Physiol Rev. (2004); 84: 1381-478.
Elif Özkök CF, Makbule Aydin ED, Erhan Babalik B, Zeynep O, Nurhan Ince C, Ihsan Kara A. Combined impact of matrix metalloproteinase-3 and paraoxonase 155/192 gene variants on coronary artery disease in Turkish patients. Medical Science Monitor. (2008); 14: 536-542.
Najafi M, Gohari LH, Firoozrai M. Paraoxonase 1 gene promoter polymorphisms are associated with the extent of stenosis in coronary arteries. Thromb Res. (2009); 123: 503-510.

TROMBOSE
Ye Z, Liu E, Higgins J, Keavney B, Lowe G, Collins R, Danesh J. Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66155 cases and 91307 controls. The Lancet.(2006); 367: 651-658.
Wu NQ, Song L, Hua YH, Lu XF, Ye J, Li JX, Gu DF, Yang YJ. Association between single nucleotide polymorphisms of matrix metalloproteinase-3 gene and the severity of coronary atherosclerosis in patients with coronary artery. Chinese journal of cardiovascular diseases. (2008); 36: 501-505.

ONTSTEKING
Wang L, Lu X, Li Y, Li F, Chen S, and Gu D. Functional analysis of the C-reactive protein (CRP) gene -717A>G polymorphism associated with coronary heart disease. BMC Medical Genetics. (2009); 10: 73.
Galkina E, Ley K. Immune and Inflammatory Mechanisms of Atherosclerosis. Annu Rev Immunol. (2009); 27: 165-197.
Riikola A, Sipilä K, Kähönen M, Jula A, Nieminen MS, Moilanen L, Kesäniemi YA, Lehtimäki T, Hulkkonen J. Interleukin-6 promoter polymorphism and cardiovascular risk factors: the Health 2000 Survey. Atherosclerosis. (2009); 207: 466-470.

LIPIDE METABOLISME
Breslow JL. Genetics of lipoprotein abnormalities associated with coronary artery disease susceptibility. Annu Rev Genet. (2000); 34: 233-254.
Pillois X, Phuong Do Thi N, Reynaud A, Benchimol D, Lagrost L, Bonnet J. TaqIB polymorphism in cholesterol ester transfer protein (CETP) gene predicts future cardiovascular death in patients experiencing an acute coronary syndrome. Clinical chemistry and laboratory medicine: CCLM / FESCC. (2009); 47: 1039-1046.

Ashok Kumar M, Subhashini NG, Sai Babu R, Ramesh A, Cherian KM, Emmanuel C. Genetic variants on apolipoprotein gene cluster influence triglycerides with a risk of coronary artery disease among Indians. Molecular biology reports. (2010); 37: 521-527.

Sarwar N, Sandhu MS, Ricketts LS, Butterworth AS, Di Angelantonio E, Boekholdt SM, Ouwehand W, Watkins H, Samani NJ, Saleheen D, Lawlor D, Reilly MP, Hingorani AD, Talmud PJ, Danesh J. Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies - Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration. The Lancet. (2010); 375: 1634–1639.

 

HOMOCYSTEINE
Choy PC, Mymin D, Zhu Q, Dakshinamurti OK. Atherosclerosis risk factors: the possible role of homocysteine. Mol Cell Biochem. (2000); 207:143-148.
Khandanpour N, Willis G, Meyer FJ, Armon MP, Loke YK, Wright AJ, Finglas PM, Jennings BA. Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis. J Vasc Surg. (2009); 49: 711-718.
Biselli PM, Guerzoni AR, de Godoy M, Eberlin MN, Haddad R, Carvalho VM, Vannucchi H, Pavarino-Bertelli EC, Goloni-Bertollo EM. Genetic polymorphisms involved in folate metabolism and concentrations of methylmalonic acid and folate on plasma homocysteine and risk of coronary artery disease. Journal of thrombosis and thrombolysis Publish.(2010); 29: 32-40.

Overig
Helgadottir A, Thorleifsson G, Manolescu A, Gretarsdottir S, Blondal T, Jonasdottir A, Sigurdsson A, Baker A, Palsson A, Masson G, Gudbjartsson DF, Magnusson KP, Andersen K, Levey AI, Backman VM, Matthiasdottir S, Jonsdottir T, Palsson S, Einarsdottir H, Gunnarsdottir S, Gylfason A, Vaccarino V, Hooper WC, Reilly MP, Granger CB, Austin H, Rader DJ, Shah SH, Quyyumi AA, Gulcher JR, Thorgeirsson G, Thorsteinsdottir U, Kong A, Stefansson K. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science. (2007); 8: 1491-1493.

Abdullah, KG et al. Four SNPs on chromosome 9p21 confer risk to premature, familial CAD and MI in an American Caucasian population (GeneQuest). Ann Hum Genet. (2008); 72: 654-657.

Ozaki K, Sato H, Inoue K, Tsunoda T, Sakata Y, Mizuno H, Lin TH, Miyamoto Y, Aoki A, Onouchi Y, Sheu SH, Ikegawa S, Odashiro K, Nobuyoshi M, Juo SH, Hori M, Nakamura Y and Tanaka T. SNPs in BRAPassociated with risk of myocardial infarction in Asian populations. Nature Genetics. (2009); 41: 329-333.

Assmann G, Cullen P, Fruchart JC, Greten H, Naruszewicz M, Olsson A, Paoletti R, Riesen W, Stoll M, Tikkanen M, von Eckardstein A; International Task Force for Prevention of Coronary Heart Disease. (2005): Implications of emerging risk factors for therapeutic intervention. Nutr Metab Cardiovasc Dis 15(5): 373-81

Ward H, Mitrou PN, Bowman R, Luben R, Wareham NJ, Khaw KT, Bingham S. (2009): APOE genotype, lipids, and coronary heart disease risk: a prospective population study. Arch Intern Med 169(15): 1424-9.

 

MET BETREKKING TOT DIABETES
Legry V, Cottel C, Ferrières J, Arveiler D, Andrieux N, Bingham A, Wagner A, Ruidavets j, Ducimetière P, Amouyel P. Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study. Metabolism, clinical and experimental. (2009); 58: 971-975.

Berthold HK, Giannakidou E, Krone W, Mantzoros CS, Gouni-Berthold I. The Leu72Met polymorphism of the ghrelin gene is associated with a decreased risk for type 2 diabetes. Clin Chim Acta. (2009); 399: 112-116.

Duarte SFP, Francischetti EA, Genelhu VA, Cabello PH, Pimentel MMG. LEPR p.Q223R, β3-AR p.W64R and LEP c.-2548G>A gene variants in obese Brazilian subjects. Genetics and Molecular Researc.  (2007); 6(4): 1035-1043.

Mammès O, Betoulle D, Aubert R, Herbeth B, Siest G, Fumeron F. Association of the G-2548A polymorphism in the 5' region of the LEP gene with overweight. Ann Hum Genet. (2000); 64(Pt 5): 391-394.

Tavridou A, Arvanitidis KI, Tiptiri-Kourpeti A, Petridis I, Ragia G, Kyroglou S, Christakidis D, Manolopoulos VG. Thr54 allele of fatty-acid binding protein 2 gene is associated with obesity but not type 2 diabetes mellitus in a Caucasian population. Diabetes Res Clin Pract. (2009); 84(2): 132-137.

Kiani JG, Saeed M, Parvez SH, Frossard PM. Association of G-protein beta-3 subunit gene (GNB3) T825 allele with Type II diabetes. Neuro Endocrinol Lett. (2005); 26(2): 87-88.

Ghoussaini M, Meyre D, Lobbens S, Charpentier G, Clément K, Charles MA, Tauber M, Weill J, Froguel P. Implication of the Pro12Ala polymorphism of the PPAR-gamma 2 gene in type 2 diabetes and obesity in the French population. BMC Med Genet. (2005); 22(6): 11.

Andrulionyte L, Kuulasmaa T, Chiasson JL, Laakso M; STOP-NIDDM Study Group. Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-alpha gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial. Diabetes. (2007); 56(4): 1181-1186.

MET BETREKKING TOT DE PROSTATEgen test
Nam RK.,December 01, 2011.,Cancer Biol Ther: New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort.

Kote-Jarai Z.,July 10, 2011.,Nat Genet:  Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

Schumacher FR.,July 08, 2011., Hum Mol Genet: Genome-wide association study identifies new prostate cancer susceptibility loci

Haiman CA., May 22, 2011., Nat Genet: Genome-wide association study of prostate cancer in men of African ancestry identifies a susceptibility locus at 17q21.

FitzGerald LM., April 05, 2011., Cancer Epidemiol Biomarkers Prev: Genome-wide association study identifies a genetic variant associated with risk for more aggressive prostate cancer.

Takata R., August 01, 2010., Nat Genet: Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population.

Eeles RA., September 20, 2009., Nat Genet: Identification of seven new prostate cancer susceptibility loci through a genome-wide association study

Gudmundsson J., September 20, 2009., Nat Genet: Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility.

Sun J., January 01, 2009., Cancer Res: Sequence variants at 22q13 are associated with prostate cancer risk.

Eeles RA., February 10, 2008., Nat Genet: Multiple newly identified loci associated with prostate cancer susceptibility.

MET BETREKKING TOT NUTRIGENOMIC
Kris-Etherton PM, Hecker KD, Bonanome A, Coval SM, Binkoski AE, Hilpert KF, Griel AE, Etherton TD. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am J Med. (2002); 113: 71S-88S.

Kris-Etherton PM, Harris WS, Appel LJ and the Nutrition Committee. Fish consumption, fish oil, omega-3 fatty acids and cardiovascular disease. Circulation.(2002); 106: 2747-2757.

Coffey M, Crowder GK and Cheek DJ. Reducing Coronary Artery Disease by decreasing homocysteine levels. Crit care Nurse.(2003); 23: 25-30.

Appel LJ, Brands MW, Daniels SR, Njeri Karanja N, Elmer PJ, Sacks FM. Dietary Approaches to Prevent and Treat Hypertension: A Scientific Statement From the American Heart Association. Hypertension. (2006); 47: 296-308.

Valtueña S, Pellegrini N, Franzini L, Bianchi MA, Ardigò D, Del Rio D, Piatti PM, Scazzina F, Zavaroni I and Brighenti F. Food selection based on total antioxidant capacity can modify antioxidant intake, systemic inflammation, and liver function without altering markers of oxidative stress. Am J Clin Nutr. (2008); 87: 1290-1297.

Corella D, Ordovas JM. Nutrigenomics in Cardiovascular Medicine. Circulation: Cardiovascular Genetics. (2009); 2: 637-651.

Budoff M & al. Aged Garlic Extract with B Vitamins, Folic Acid and L-Arginine Retards the Progression of Subclinical Atherosclerosis. Preventive Med. (2009); 49: 101-107.
Ghanim H, Sia CL, Abuaysheh S, Korzeniewski K, Patnaik P, Marumganti A, Chaudhuri A and Dandona P. An Anti-inflammatory and Reactive Oxygen Species Suppressive Effects of an Extract of Polygonum Cuspidatum Containing Resveratrol. J Clin Endocrinol Metab. (2010); 95: E1-E8.

Camargo A, Ruano J, Fernandez JM, Parnell LD, Jimenez A, Santos-Gonzalez M, Marin C, Perez-Martinez P, Uceda M, Lopez-Miranda J and Perez-Jimenez F. Gene expression changes in mononuclear cells in patients with metabolic syndrome after acute intake of phenol-rich virgin olive oil. BMC Genomics. (2010); 11: 253.

MET BETREKKING TOT LIFESTYLE
Bernstein MS, Costanza MC, James RW, Morris MA, Cambien F, Raoux S, Morabia A. Physical Activity May Modulate Effects of ApoE Genotype on Lipid Profile. Arteriosclerosis, Thrombosis, and Vascular Biology.(2002); 22: 133-140.
Iestra JA, Kromhout D, Van Der Schouw V, Grobbee DE, Boshuizen HC, Van Staveren WA. Effect Size Estimates of Lifestyle and Dietary Changes on All-Cause Mortality in Coronary Artery Disease Patients. Circulation.(2005); 112: 924-934.

MET BETREKKING TOT WELL-BEING
GEWICHTSCONTROLE
Razquin C, Marti A, Martinez JA. (2011): Evidences on three relevant obesogenes: MC4R, FTO and PPARγ. Approaches for personalized nutrition. Mol Nutr Food Res 55(1): 136-49
Hainer V, Zamrazilová H, Spálová J, Hainerová I, Kunesová M, Aldhoon B, Bendlová B. (2008): Role of hereditary factors in weight loss and its maintenance. Physiol Res 57 Suppl 1: S1-15

ONTGIFTIGING (DETOXIFICATIE)
Habdous, M., Siest, G., Herbeth, B., et al., (2004): Glutathione S-transferases genetic polymorphisms and human diseases: overview of epidemiological studies Ann. Biol. Clin. (Paris) 62(1): 15-24
Chuang CY, Chang CC. (2007): Urinary 1-hydroxypyrene level relative to vehicle exhaust exposure mediated by metabolic enzyme polymorphisms. J Occup Health 49(2): 150-51

LICHAMELIJKE FITNESS
Ostrander EA, Huson HJ, Ostrander GK. (2009): Genetics of athletic performance. Annu Rev Genomics Hum Genet 10: 407-29
Caló MC, Vona G. (2008): Gene polymorphisms and elite athletic performance. J Anthropol Sci 86: 113-31

MENTALE FITNESS
Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericak-Vance MA, Risch N, van Duijn CM. (1997): Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 278(16): 1349-56
Xu X, Breen G, Chen CK, Huang YS, Wu YY, Asherson P. (2010): Association study between a polymorphism at the 3'-untranslated region of CLOCK gene and attention deficit hyperactivity disorder. Behav Brain Funct 6: 48

GEZONDE BOTTEN
Trouvin AP, Goëb V. (2010): Receptor activator of nuclear factor-κB ligand and osteoprotegerin: maintaining the balance to prevent bone loss. Clin Interv Aging 5: 345
Uitterlinden AG, Fang Y, Van Meurs JB, Pols HA, Van Leeuwen JP. (2004): Genetics and biology of vitamin D receptor polymorphisms. Gene 338(2): 143-56
Ioannidis JP, Stavrou I, Trikalinos TA, Zois C, Brandi ML, Gennari L, Albagha O, Ralston SH, Tsatsoulis A; ER-alpha Genetics Meta-Analysis. (2002): Association of polymorphisms of the estrogen receptor alpha gene with bone mineral density and fracture risk in women: a meta-analysis. J Bone Miner Res 17(11): 2048-60

GEZONDE HUID
Fisher GJ, Kang S, Varani J, Bata-Csorgo Z, Wan Y, Datta S, Voorhees JJ. (2002): Mechanisms of photoaging and chronological skin aging. Arch Dermatol 138(11): 1462-70
Rodríguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ, Irvine AD, Weidinger S. (2009): Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease. J Allergy Clin Immunol 123(6): 1361-70.e7

GEZONDE TANDEN
Wagner J, Kaminski WE, Aslanidis C, Moder D, Hiller KA, Christgau M, Schmitz G, Schmalz G. (2007): Prevalence of OPG and IL-1 gene polymorphisms in chronic periodontitis. J Clin Periodontol 34(10): 823-7
Shao MY, Huang P, Cheng R, Hu T. (2009): Interleukin-6 polymorphisms modify the risk of periodontitis: a systematic review and meta-analysis. J Zhejiang Univ Sci B 10(12): 920-7

MET BETREKKING TOT PHARMACOGENETICA
ToffoliI G, Russo A, Innocenti F, Corona G, Tumolo S, Sartor F, Mini F and Boiocchi M. Effect of methylenetetrahydrofolate reductase C677T polymorphism on toxicity and homocysteine plasma level after chronic methotrexate treatment of ovarian cancer. Int. J. Cancer. (2003); 103: 294-299.

Regieli JJ, Jukema JW, Grobbee DE, Kastelein JJP, Kuivenhoven JA, Zwinderman AH, Van der Graaf Y, Bots ML and Doevendans PA. CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction. European Heart Journal. (2008); 29: 2792-2799.

Peters BJM, Klungel OH, de Boer A, Stricker BH and Maitland-Van Der Zee AH. Pharmacogenetics of cardiovascular drug therapy. Clin Cases Miner Bone Metab. (2009); 6: 55-65.

Yang YY, Lin HC, Lin MW, Chu CJ, Lee FY, Hou MC, Lee SD, Lee WP, Liu TT and Jap TS. Identification of diuretic non-responders with poor long-term clinical outcomes: a 1-year follow-up of 176 non-azotaemic cirrhotic patients with moderate ascites. Clinical Science. (2011); 121: 509-521.

MET BETREKKING TOT TELOMEREN
Chen R et al. (2012). "Personal omics profiling reveals dynamic molecular and medical phenotypes." Cell. Mar 16;148(6):1293-307.

Prather AA et al. (2011). "Shorter leukocyte telomere length in midlife women with poor sleep quality." J Aging Res. 2011:721390.

Wills LP et al. (2011). "Telomeres and telomerase in renal health." J Am Soc Nephrol. Jan;22(1):39-41.

Donate LE et al. (2011). “Telomeres in cancer and ageing.” Phil. Trans. R. Soc. B 366,76-84.

Bernardes de Jesus B et al. (2010). “Aging by Telomere Loss Can Be Reversed.” Cell Stem Cell 8(1):3-4.

Flores I et al. (2008). ”The longest telomeres: a general signature of adult stem cell compartments.” Genes & Development 22(5):654-67.

Ornish D et al. (2008). “Increased telomerase activity and comprehensive lifestyle changes: a pilot study.” Lancet Oncol. Nov;9(11):1048-57.
www.ncbi.nlm.nih.gov/pubmed/18799354

Pérez - Rivero G et al. (2008). “Telomerase deficiency promotes oxidative stress by reducing catalase activity.” Free Radic. Biol. Med. 45(9):1243-51.

Canela A et al. (2007). ”High-throughput telomere length quantification by FISH and its application to human population studies.” Proc. Natl. Acad. Sci. 104(13):5300-5.
Collado M et al. (2007). “Cellular senescence in cancer and aging.” Cell 130(2):223-233.

García CK et al. (2007). “Human diseases of telomerase dysfunction: insights into tissue aging.” Nucleic. Acid Res. 35(22):7406-7416.

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